反应详情

温度

50 °C

There was added 50 ml of a mixture of acetic acid, THF and water (3:1:1) to 3.26 g (10.4 mml) of (-)-3-t-butyldimethylsilyloxybutyric acid phenylthioester and the mixture was stirred at 50° C. for 24 hours. The obtained reaction mixture was concentrated and distilled at 128° to 130° C. under a pressure of 0.8 mmHg to give 1.91 g of (-)-3-hydroxybutyric acid phenylthioester.

1. customThe obtained reaction mixture
2. concentrationwas concentrated
3. distillationdistilled at 128° to 130° C. under a pressure of 0.8 mmHg