4-Aminobenzonitrile → HCID 178510046, compound

HRID 24779Notes

Reaction equation

HRID 24779 reaction equation
C([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[C:6](=[C:13](OCC)[C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:5]1=[O:23])(=O)C.[NH2:24][C:25]1[CH:32]=[CH:31][C:28]([C:29]#[N:30])=[CH:27][CH:26]=1.[OH-].[Na+]>CN(C=O)C>[C:29]([C:28]1[CH:31]=[CH:32][C:25]([NH:24]/[C:13](=[C:6]2\[C:5](=[O:23])[NH:4][C:12]3[C:7]\2=[CH:8][CH:9]=[CH:10][CH:11]=3)/[C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=2)=[CH:26][CH:27]=1)#[N:30]

Participants

5

Reactant 3

HCID 133964-AminobenzonitrileHCID 14798Sodium HydroxideHCID 542378881-Acetyl-3-(1-ethoxy-1-phenylmethylidene}-2-indolinone

Product 1

HCID 178510046HCID 178510046, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Prepared analogously to Example 1 from 1-acetyl-3-(1-ethoxy-1-phenyl-methylidene)-2-indolinone and 4-aminobenzonitrile in DMF and subsequent treatment with sodium hydroxide solution.

Sources & evidence

ORD record
ord-c0d95bc40a6d440cb231222a1bec02b3
Source dataset
uspto-grants-2005_02
Patent number
US06855710B2

Reaction notes

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