反应详情

To a mixture of 10 g of product from Example 67, 0.0965 g of dimethylformamide and 150 ml of methylene chloride is added dropwise 3.46 ml of oxalyl chloride. The reaction is stirred at room temperature for 20 hours and the solvent concentrated in vacuo. The residue is dissolved in diethyl ether, filtered and concentrated in vacuo to give 10.5 g of the desired product as colorless needles.

1. concentrationthe solvent concentrated in vacuo
2. dissolutionThe residue is dissolved in diethyl ether
3. filtrationfiltered
4. concentrationconcentrated in vacuo