反应详情

温度

50 °C

To a solution of 4,4'-dichlorobenzophenone (2.51 g) in isopropyl alcohol (15 ml) was added sodium borohydride (0.45 g). The mixture was stirred for 4 hours at 50° C. and poured into diluted hydrochloric acid (60 ml). The organic layer was extracted with ethyl acetate (20 ml) and washed with water (30 ml×2). The solution was dried over magnesium sulfate. The solvent was removed in vacuo to give colorless oil of bis(4-chlorophenyl)methanol (2.50 g).

1. extractionThe organic layer was extracted with ethyl acetate (20 ml)
2. washwashed with water (30 ml×2)
3. dry with materialThe solution was dried over magnesium sulfate
4. customThe solvent was removed in vacuo