Hydrochloric Acid → HCID 67693235, compound

HRID 249182Notes

Reaction equation

HRID 249182 reaction equation
[ClH:1].[CH2:2]([C:6]1[CH:11]=[CH:10][C:9]([CH:12]([NH:23][C:24]2[CH:25]=[C:26]([CH:44]=[CH:45][CH:46]=2)[C:27]([C:29]2[C:37]3[C:32](=[CH:33][CH:34]=[CH:35][CH:36]=3)[N:31]([CH2:38][CH2:39][CH2:40][C:41]([OH:43])=[O:42])[CH:30]=2)=[O:28])[C:13]2[CH:18]=[CH:17][C:16]([CH2:19][CH:20]([CH3:22])[CH3:21])=[CH:15][CH:14]=2)=[CH:8][CH:7]=1)[CH:3]([CH3:5])[CH3:4]>C(OCC)(=O)C>[ClH:1].[CH2:19]([C:16]1[CH:17]=[CH:18][C:13]([CH:12]([NH:23][C:24]2[CH:25]=[C:26]([CH:44]=[CH:45][CH:46]=2)[C:27]([C:29]2[C:37]3[C:32](=[CH:33][CH:34]=[CH:35][CH:36]=3)[N:31]([CH2:38][CH2:39][CH2:40][C:41]([OH:43])=[O:42])[CH:30]=2)=[O:28])[C:9]2[CH:8]=[CH:7][C:6]([CH2:2][CH:3]([CH3:5])[CH3:4])=[CH:11][CH:10]=2)=[CH:14][CH:15]=1)[CH:20]([CH3:21])[CH3:22]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 178077FK 143

Product 1

HCID 67693235HCID 67693235, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent2×

Procedure

A solution of 4N-hydrogen chloride (1.5 ml) in ethyl acetate was added to a solution of 4-[3-[3-[bis(4-isobutylphenyl)methylamino]benzoyl]indol-1-yl]butyric acid (3.0 g) in ethyl acetate (15 ml). The mixture was refrigerated for 16 hours to give 4-[3-[3-[bis(4-isobutylphenyl)methylamino]benzoyl]indol-1-yl]butyric acid hydrochloride as yellow crystals (3.1 g).

Sources & evidence

ORD record
ord-d7d30f36c50048d0af91d2319e19cf89
Source dataset
uspto-grants-1993_05
Patent number
US05212320

Reaction notes

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