Thionyl Chloride → 7-Octyl-2-fluorenecarbonyl chloride

HRID 249216Notes

Reaction equation

HRID 249216 reaction equation
[CH2:1]([C:9]1[CH:21]=[C:20]2[C:12]([C:13]3[CH:14]=[CH:15][C:16]([C:22]([OH:24])=O)=[CH:17][C:18]=3[CH2:19]2)=[CH:11][CH:10]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].S(Cl)([Cl:27])=O>CN(C)C=O>[CH2:1]([C:9]1[CH:21]=[C:20]2[C:12]([C:13]3[CH:14]=[CH:15][C:16]([C:22]([Cl:27])=[O:24])=[CH:17][C:18]=3[CH2:19]2)=[CH:11][CH:10]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]

Participants

4

Reactant 2

HCID 24386Thionyl Chloride2×HCID 197606567-Octyl-2-fluorenecarboxylic acid

Product 1

HCID 197606657-Octyl-2-fluorenecarbonyl chloride

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

To 0.70 g (2.17 mM) of 7-octyl-2-fluorenecarboxylic acid, 2.1 ml of thionyl chloride and a drop of N,N-dimethylformamide (DMF) were added, followed by heat-refluxing for 20 minutes under stirring. After the reaction, an excessive thionyl chloride was distilled-off under reduced pressure to obtain 7-octyl-2-fluorenecarbonyl chloride.

Workup

  1. temperatureby heat-refluxing for 20 minutes
  2. customAfter the reaction

Sources & evidence

ORD record
ord-bdc31afe4ec04e90a1722c547477e910
Source dataset
uspto-grants-1993_05
Patent number
US05213709

Reaction notes

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