反应详情

2.2 ml of (20 mmol) of 4-fluoronitrobenzene and 2.6 ml (24 mmol) of N,N-dimethylethylene-diamine are heated in 10 ml of ethanol at 120° C. in a microwave oven for 1.5 hours. Then 50 ml of 1 N hydrochloric acid are added. The reaction solution is washed with ethyl acetate. Then the aqueous phase is combined with 4 N sodium hydroxide solution until an alkaline reaction is obtained and extracted with ethyl acetate.

1. washThe reaction solution is washed with ethyl acetate
2. customThen the aqueous phase is combined with 4 N sodium hydroxide solution until an alkaline reaction
3. customis obtained
4. extractionextracted with ethyl acetate