Phenylhydrazine → HCID 178423470, compound

HRID 249680Notes

Reaction equation

HRID 249680 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([CH3:12])[CH:10]=2)[N:5]=[CH:4][C:3]=1[C:13]([O:15]CC)=O.[C:18]1([NH:24][NH2:25])[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>>[CH3:12][C:9]1[CH:8]=[CH:7][C:6]2[NH:5][CH:4]=[C:3]3[C:13](=[O:15])[N:24]([C:18]4[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=4)[N:25]=[C:2]3[C:11]=2[CH:10]=1

Participants

3

Reactant 2

HCID 7516PhenylhydrazineHCID 1479091ethyl 4-chloro-6-methylquinoline-3-carboxylate

Product 1

HCID 178423470HCID 178423470, compound

Procedure

The title compound was prepared following the procedure described in Step 3 using 3f and phenyl hydrazine. 1H NMR (DMSO-d6) δ (ppm): 2.46 (3H, s), 7.16 (1H, t, J=7.41 Hz), 7.41 (2H, dd, J=8.51, 7.14 Hz), 7.46 (1H, dd, J=8.52, 1.92 Hz), 7.58 (1H, d, J=8.51 Hz), 8.00 (1H, br), 8.21 (2H, dd, J=7.69, 1.10 Hz), 8.66 (1H, s). m/z 276.3 (MH+).

Sources & evidence

ORD record
ord-2ef644655dfb4354926cb434c8657da6
Source dataset
uspto-grants-2011_01
Patent number
US07863266B2

Reaction notes

Loading…