反应详情

温度

80 °C

A mixture of 0.45 g (1.17 mmol) of the starting material I, 0.46 g (2.36 mmol) of ethyl bromopyruvate and 7 ml of dimethylformamide was stirred at 80° C. for 30 min. After cooling the precipitated crystals were filtered off, washed with ethanol and dried to yield 0.41 g (85%) of the title compound; Mp.: 242-243° C.

1. temperatureAfter cooling the precipitated crystals
2. filtrationwere filtered off
3. washwashed with ethanol
4. customdried