Hydrochloric Acid → HCID 58089228, compound

HRID 251385Notes

Reaction equation

HRID 251385 reaction equation
[C:1]([O:10]C(=O)CCCCC)(=[O:9])[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[OH:4].[OH-:18].[Na+].Cl>CCO.O>[C:7]([C:7]1[CH:8]=[C:2]([C:1]([OH:10])=[O:9])[C:3]([OH:4])=[CH:5][CH:6]=1)(=[O:18])[CH2:8][CH2:2][CH2:3][CH3:5]

Participants

6

Reactant 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 86610722HCID 86610722, compound

Product 1

HCID 58089228HCID 58089228, compoundYield 90%

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 962WaterSolvent

Procedure

97.5 g of compound 17 (412 mmole) was dissolved in 530 ml EtOH and 1050 ml water. 87 g NaOH (2.19 mole) was added and the mixture was refluxed for 5 hours. Afterwards the mixture was acidified with concentrated HCl to pH 1. The formed precipitate was filtered off and dried under reduced pressure. 82 g was obtained (90% yield).

Workup

  1. temperaturethe mixture was refluxed for 5 hours
  2. filtrationThe formed precipitate was filtered off
  3. customdried under reduced pressure
  4. custom82 g was obtained (90% yield)

Sources & evidence

ORD record
ord-6919084bb0a146e89da8ea9d1ad33415
Source dataset
uspto-grants-2011_01
Patent number
US07863428B2

Reaction notes

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