Hydrochloric Acid → HCID 66888418, compound

HRID 252389Notes

Reaction equation

HRID 252389 reaction equation
C(OC([N:8]1[CH2:13][CH2:12][CH2:11][C@H:10]([C:14]([C:17]([O:19][CH3:20])=[O:18])([CH3:16])[CH3:15])[CH2:9]1)=O)(C)(C)C.[ClH:21]>O1CCOCC1>[ClH:21].[CH3:20][O:19][C:17](=[O:18])[C:14]([CH3:15])([C@H:10]1[CH2:11][CH2:12][CH2:13][NH:8][CH2:9]1)[CH3:16]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 66889038HCID 66889038, compound

Product 1

HCID 66888418HCID 66888418, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

1.030 g of (R)-3-(1-methoxycarbonyl-1-methyl-ethyl)-piperidine-1-carboxylic acid tert-butyl ester are taken up in 10 ml of 4M HCl in dioxane. The reaction solution is left to stand at room temperature for 1 hour and is then concentrated under reduced pressure to provide the title compound as colourless solid which can be used without further purification.

Workup

  1. waitThe reaction solution is left
  2. concentrationis then concentrated under reduced pressure

Sources & evidence

ORD record
ord-e8a6ff54f6964407a00170b3a372fbae
Source dataset
uspto-grants-2011_01
Patent number
US07868036B2

Reaction notes

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