1-Methylpiperazine → HCID 178480622, compound

HRID 252954Notes

Reaction equation

HRID 252954 reaction equation
[NH:1]1[C:13]2[C:12]3[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=3[N:6]=[CH:5][C:4]=2[C:3](=[O:14])[NH:2]1.[CH3:15][N:16]1[CH2:21][CH2:20][NH:19][CH2:18][CH2:17]1>>[CH3:15][N:16]1[CH2:21][CH2:20][N:19]([C:9]2[CH:10]=[CH:11][C:12]3[C:13]4[C:4]([C:3](=[O:14])[N:2]([C:7]5[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=5)[N:1]=4)=[CH:5][NH:6][C:7]=3[CH:8]=2)[CH2:18][CH2:17]1

Participants

3

Reactant 2

HCID 531671-MethylpiperazineHCID 3179913H-Pyrazolo[4,3-c]quinolin-3-one, 2,5-dihydro-

Product 1

HCID 178480622HCID 178480622, compound

Procedure

The title compound was prepared following the procedure in Step 5 using 13a and 1-methylpiperazine. 1H-NMR (CD3OD) δ (ppm): 2.44 (3H, s), 2.74 (4H, brm), 3.44 (4H, brm), 7.03 (1H, d, J=2.20 Hz), 7.27 (1H, ddd, J=7.41, 1.64, 1.10 Hz), 7.35 (1H, dd, J=9.07, 2.47 Hz), 7.65 (2H, m), 7.99 (2H, m), 8.17 (1H, d, J=9.07 Hz), 8.53 (1H, s). m/z 360.4 (MH+).

Sources & evidence

ORD record
ord-d74bb6ca1cc34548aca8cf83e116febc
Source dataset
uspto-grants-2011_01
Patent number
US07872002B2

Reaction notes

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