反应详情

温度

90 °C

5-(4-Chloro-benzyloxy)-2-hydroxymethyl-pyran-4-one (71, 8.00 g, 3.00 mmol) was suspended in ammonium hydroxide (200 mL) in an 80 mL sealed tube. The reaction was heated at 90° C. overnight. Upon cooling, the reaction was lowered to pH 10 with 6N HCl to provide a beige solid that was collected by filtration (72, 7.8 g, 98%).

1. customsealed tube
2. temperatureUpon cooling
3. customto provide a beige solid
4. filtrationthat was collected by filtration (72, 7.8 g, 98%)