反应详情

温度

0 °C

A solution of 2,3-di(carboxymethyl)furan (35 mmol) in THF (400 mL) is cooled to 0° C. and treated with BH3.THF (174 mmol) over 10 minutes, and stirred for an additional 20 minutes at 0° C. before warming to room temperature overnight. The crude reaction is poured over saturated aqueous NaHCO3 and extracted with ethyl acetate. The organic layer is dried and concentrated to give 2,3-di(2-hydroxyethyl)furan.

1. temperaturebefore warming to room temperature overnight
2. customThe crude reaction
3. extractionextracted with ethyl acetate
4. customThe organic layer is dried
5. concentrationconcentrated