p-Toluenesulfonic acid → HCID 178448989, compound

HRID 254585Notes

Reaction equation

HRID 254585 reaction equation
[F:1][C:2]1[CH:9]=[C:8]([O:10][CH3:11])[CH:7]=[C:6]([F:12])[C:3]=1[CH:4]=O.[CH2:13]([NH2:17])[CH2:14][CH2:15][CH3:16].C1(C)C=CC(S(O)(=O)=O)=CC=1>>[CH2:13](/[N:17]=[CH:4]/[C:3]1[C:2]([F:1])=[CH:9][C:8]([O:10][CH3:11])=[CH:7][C:6]=1[F:12])[CH2:14][CH2:15][CH3:16]

Participants

4

Reactant 3

HCID 6101p-Toluenesulfonic acidHCID 8007ButylamineHCID 37037132,6-Difluoro-4-methoxybenzaldehyde

Product 1

HCID 178448989HCID 178448989, compound

Procedure

Butyl-[1-(2,6-difluoro-4-methoxy-phenyl)-meth-(E)-ylidene]-amine was prepared from 2,6-difluoro-4-methoxybenzaldehyde, N-butylamine and p-toluenesulphonic acid in analogy to Example 186a): yellow oil; MS (ISP): 228.4 ([M+H]+, 100%).

Sources & evidence

ORD record
ord-89ca1caf69ef4874afa0b8ff8cae7330
Source dataset
uspto-grants-2011_01
Patent number
US07875645B2

Reaction notes

Loading…