Trifluoroacetic acid → HCID 24779853, compound

HRID 254586Notes

Reaction equation

HRID 254586 reaction equation
[CH2:1]([C:3]1[CH:8]=[C:7]([O:9][CH3:10])[CH:6]=[C:5]([CH2:11][CH3:12])[C:4]=1[CH:13]([C:15]1[NH:16][CH:17]=[CH:18][N:19]=1)O)[CH3:2].C([SiH](CC)CC)C.FC(F)(F)C(O)=O>>[CH2:1]([C:3]1[CH:8]=[C:7]([O:9][CH3:10])[CH:6]=[C:5]([CH2:11][CH3:12])[C:4]=1[CH2:13][C:15]1[NH:19][CH:18]=[CH:17][N:16]=1)[CH3:2]

Participants

4

Reactant 3

HCID 6422Trifluoroacetic acidHCID 12052TriethylsilaneHCID 58951730HCID 58951730, compound

Product 1

HCID 24779853HCID 24779853, compound

Procedure

2-(2,6-Diethyl-4-methoxy-benzyl)-1H-imidazole was prepared from rac-(2,6-diethyl-4-methoxy-phenyl)-(1H-imidazol-2-yl)-methanol, triethylsilane and trifluoroacetic acid in analogy to Example 191e): white crystals; MS (ISP): 245.4 ([M+H]+, 100%).

Sources & evidence

ORD record
ord-7266530fa9a745d4aed57e4ca9d1cf12
Source dataset
uspto-grants-2011_01
Patent number
US07875645B2

Reaction notes

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