Trifluoroacetic acid → HCID 24779983, compound

HRID 254596Notes

Reaction equation

HRID 254596 reaction equation
[CH2:1]([O:3][C:4]1[C:5]([CH2:19][CH3:20])=[C:6]([CH:12]([C:14]2[NH:15][CH:16]=[CH:17][N:18]=2)O)[C:7]([CH2:10][CH3:11])=[CH:8][CH:9]=1)[CH3:2].C([SiH](CC)CC)C.FC(F)(F)C(O)=O>>[CH2:1]([O:3][C:4]1[C:5]([CH2:19][CH3:20])=[C:6]([C:7]([CH2:10][CH3:11])=[CH:8][CH:9]=1)[CH2:12][C:14]1[NH:18][CH:17]=[CH:16][N:15]=1)[CH3:2]

Participants

4

Reactant 3

HCID 6422Trifluoroacetic acidHCID 12052TriethylsilaneHCID 58951685HCID 58951685, compound

Product 1

HCID 24779983HCID 24779983, compound

Procedure

2-(3-Ethoxy-2,6-diethyl-benzyl)-1H-imidazole was prepared from rac-(3-ethoxy-2,6-diethyl-phenyl)-(1H-imidazol-2-yl)-methanol, triethylsilane and trifluoroacetic acid in analogy to Example 191e): light yellow crystals; MS (ISP): 259.3 ([M+H]+, 100%).

Sources & evidence

ORD record
ord-1f0f224d420f4ea9a79b653fd08a5162
Source dataset
uspto-grants-2011_01
Patent number
US07875645B2

Reaction notes

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