Methanol → HCID 70450173, compound

HRID 255479Notes

Reaction equation

HRID 255479 reaction equation
C[O:2][C:3](=[O:18])[C:4]([C:10]1[CH:15]=[CH:14][C:13]([Cl:16])=[C:12]([Cl:17])[CH:11]=1)([OH:9])[C:5](OC)=[O:6].[CH3:19][NH2:20].[CH3:21]O>>[CH3:19][N:20]([CH3:21])[C:5](=[O:6])[C:4]([C:10]1[CH:15]=[CH:14][C:13]([Cl:16])=[C:12]([Cl:17])[CH:11]=1)([OH:9])[C:3]([OH:2])=[O:18]

Participants

4

Reactant 3

HCID 887MethanolHCID 6329MethylamineHCID 13361971HCID 13361971, compound

Product 1

HCID 70450173HCID 70450173, compound

Procedure

14.7 g of 3,4-dichlorophenylhydroxymalonic acid dimethyl ester were dissolved in 100 ml of methanol, and methylamine was passed in at 60° C. for 1 hour. The mixture was concentrated completely and the crystalline residue was recrystallised from 100 ml of ethanol. 12 g of 3,4-dichlorophenylhydroxymalonic acid dimethylamide (melting point=158°-160° C.) were obtained.

Workup

  1. concentrationThe mixture was concentrated completely
  2. customthe crystalline residue was recrystallised from 100 ml of ethanol

Sources & evidence

ORD record
ord-a16eeed6aff444b8b8b920f2ee6fae92
Source dataset
uspto-grants-1987_10
Patent number
US04698333

Reaction notes

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