Methane → HCID 23713893, compound

HRID 255850Notes

Reaction equation

HRID 255850 reaction equation
[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4]([C:11]([OH:13])=[O:12])=[CH:3][N:2]=1.C(=O)([O-])[O-].[K+:18].[K+].C>O>[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4]([C:11]([O-:13])=[O:12])=[CH:3][N:2]=1.[K+:18]

Participants

5

Reactant 3

HCID 297MethaneHCID 11430Potassium CarbonateHCID 89099Cinnoline-4-carboxylic acid

Product 1

HCID 23713893HCID 23713893, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

5.10 g of (1) was added over 30 minutes to a vigorously stirred solution of 2.02 g of potassium carbonate in 25 ml of water, at room temperature. The resulting mixture was stirred for one hour at room temperature, then treated with charcoal, and after filtration the water was evaporated. The residue was azeotropically distilled with toluene and dried at 70° C. under reduced pressure, to give 2, as a light tan powder, m.p.: above 280° C.

Workup

  1. filtrationafter filtration the water
  2. customwas evaporated
  3. distillationThe residue was azeotropically distilled with toluene
  4. customdried at 70° C. under reduced pressure
  5. customto give 2

Sources & evidence

ORD record
ord-632b0bd614004c9991480866be241a31
Source dataset
uspto-grants-1987_10
Patent number
US04699651

Reaction notes

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