反应详情

温度

135 °C

Five grams (31.5 mmol) of 3-nitro-4-chloropyridine was mixed with 26 g of ammonium acetate, and the mixture was heated at 130-140° C. for 3 hours. The mixture was allowed to cool, and then adjusted to pH 10 with concentrated aqueous ammonia. The precipitated powder was collected by filtration to obtain 2.6 g of the intended yield: 59%).

1. temperatureto cool
2. filtrationThe precipitated powder was collected by filtration
3. customto obtain 2.6 g of the intended yield: 59%)