Hydrochloric Acid → HCID 19781545, compound

HRID 257753Notes

Reaction equation

HRID 257753 reaction equation
[ClH:1].[C:2]1([CH:8]([C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[N:9]2[CH2:14][CH2:13][N:12]([C:15]3[N:16]=[CH:17][C:18]4[CH2:23][C:22](=[O:24])[N:21]([CH3:25])[C:19]=4[N:20]=3)[CH2:11][CH2:10]2)[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>C(O)C.C(Cl)Cl>[ClH:1].[C:26]1([CH:8]([C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)[N:9]2[CH2:10][CH2:11][N:12]([C:15]3[N:16]=[CH:17][C:18]4[CH2:23][C:22](=[O:24])[N:21]([CH3:25])[C:19]=4[N:20]=3)[CH2:13][CH2:14]2)[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 15170433HCID 15170433, compound

Product 1

HCID 19781545HCID 19781545, compoundYield 90%

Reagents, catalysts & solvents 1

HCID 21584144Dichloromethane ethanolSolvent

Procedure

Concentrated hydrochloric acid (0.23 g; 2.2 mmoles) was added to an ethanol/methylene chloride solution of 2-(4-diphenylmethylpiperazino)-5,6-dihydro-7-methyl-6-oxo(7H)pyrrolo[2,3-d]pyrimidine, and the solution was stirred at room temperature for 1 hour. The solvent was then evaporated under reduced pressure. The residue was washed with ether to give 0.88 g (yield 90%).

Workup

  1. customThe solvent was then evaporated under reduced pressure
  2. washThe residue was washed with ether
  3. customto give 0.88 g (yield 90%)

Sources & evidence

ORD record
ord-ab98bb173ebc4a8d8b021fb4cd6acf9b
Source dataset
uspto-grants-1993_11
Patent number
US05264435

Reaction notes

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