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HRID258050

反应详情

EQUATION

反应方程式

HRID 258050 的结构方程式

REACTANTS

反应物

3
结构：CCOC(=O)CC(=O)OCC
HCID7761

Diethyl propanedioate

C7H12O4

结构：C1CCC2=NCCCN2CC1
HCID81184

1,8-Diazabicyclo[5.4.0]undec-7-ene

C9H16N2

结构：CC(C)(C)c1cc(C(=O)c2cc3c(cc2O)CCC3)cc(C(C)(C)C)c1O
HCID19936580

未命名化合物

PRODUCTS

生成物

1
结构：CCOC(=O)c1c(-c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)c2cc3c(cc2oc1=O)CCC3
HCID19782167

未命名化合物

收率 87.8%

PROCEDURE

实验过程

A mixture of 5-(3,5-di-tert-butyl-4-hydroxybenzoyl)-6-hydroxyindan (2.8 g), diethyl malonate (3.6 g) and DBU (0.12 ml) was heated at 160°-170° C. for 2 hours. After cooling, the resulting crystals were collected by filtration and washed with ethanol to give ethyl 4-(3,5-di-tert-butyl-4-hydroxyphenyl)-2-oxo-2,6,7,8-tetrahydrocyclopenta[g][1]benzopyran-3-carboxylate (3.1 g, 87.8%). Recrystallization from ethanol gave colorless prisms, m.p. 208°-209° C.

WORKUP

后处理

  1. temperaturewas heated at 160°-170° C. for 2 hours
  2. temperatureAfter cooling
  3. filtrationthe resulting crystals were collected by filtration
  4. washwashed with ethanol