反应详情

A representative preparation was done as follows: Dimethyl aminoterephthalate (5 g), cetyltrimethyl ammonium bromide catalyst (0.05 g) and aqueous NaOH solution (5%, 300 ml) were taken in a 500 ml round bottom flask, and heated to and held at about 60° C. for about 2 hours. The mixture was then cooled to about 15°-20° C., and acidified with concentrated HCl when the acid of Formula 3 separated as yellow crystals. This was filtered, washed with ice cold water, and dried (yield: 89%).

1. customA representative preparation
2. temperatureheated to and
3. temperatureThe mixture was then cooled to about 15°-20° C.
4. customseparated as yellow crystals
5. filtrationThis was filtered
6. washwashed with ice cold water
7. customdried (yield: 89%)