Triphenylphosphine → HCID 22446990, compound

HRID 258281Notes

Reaction equation

HRID 258281 reaction equation
[F:1][C:2]([F:12])([F:11])[C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=1)[CH2:6][Br:7].[C:13]1([P:19]([C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>C1(C)C=CC=CC=1>[Br-:7].[F:1][C:2]([F:12])([F:11])[C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=1)[CH2:6][P+:19]([C:20]1[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=1)([C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1)[C:13]1[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=1

Participants

4

Reactant 2

HCID 11776TriphenylphosphineHCID 1230611-(Bromomethyl)-3-(trifluoromethyl)benzene

Product 1

HCID 22446990HCID 22446990, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

A solution of 3-trifluoromethylbenzylbromide (4.6 g, 0.019 mol) and triphenylphosphine (5.0 g, 0.019 mol) in dry toluene (200 mL) was heated to reflux for two hours. The precipitate was filtered off by suction, washed with toluene, and dried in vacuo.

Workup

  1. temperatureto reflux for two hours
  2. filtrationThe precipitate was filtered off by suction
  3. washwashed with toluene
  4. customdried in vacuo

Sources & evidence

ORD record
ord-4dd6f185958a426581467bc4c5fc3c0e
Source dataset
uspto-grants-1993_11
Patent number
US05266593

Reaction notes

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