反应详情

A solution of isoquinoline(10 g) and desylbromide (10 g) in dry benzene (50 ml) was stirred at 40° for seven hours. The suspension was allowed to stand overnight, and the benzene solution decanted off. The solid was ground to a powder, washed well with ether, and dried. Yield 12.3 g (85%), m.p. 239°-241° (Found C 68.3; H 4.6; N 3.4, Required C 68.3; H 4.5; N 3.5).

1. customthe benzene solution decanted off
2. washwashed well with ether
3. customdried