Hydrochloric Acid → 1-Decylpiperazine

HRID 259067Notes

Reaction equation

HRID 259067 reaction equation
C(OC([N:6]1[CH2:11][CH2:10][N:9]([CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21])[CH2:8][CH2:7]1)=O)C.Cl>>[CH2:12]([N:9]1[CH2:8][CH2:7][NH:6][CH2:11][CH2:10]1)[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 228932Ethyl 4-decylpiperazine-1-carboxylate

Product 1

HCID 2305441-Decylpiperazine

Procedure

53.4 Grams of 1-ethoxycarbonyl-4-decylpiperazine is combined with 300 ml. of concentrated hydrochloric acid and refluxed with stirring under a nitrogen atmosphere for approximately 48 hours. After cooling to room terperature the solvents are removed under reduced pressure. The resulting solid is suspended in ethanol, filtered, and air-dried to yield 1-decylpiperazine.

Workup

  1. temperatureAfter cooling to room terperature the solvents
  2. customare removed under reduced pressure
  3. filtrationfiltered
  4. customair-dried

Sources & evidence

ORD record
ord-bd9b7411d6924eb29a953337af8e2986
Source dataset
uspto-grants-1977_07
Patent number
US04036828

Reaction notes

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