Potassium Acetate → HCID 22798535, compound

HRID 259159Notes

Reaction equation

HRID 259159 reaction equation
[CH3:1][Si:2]([CH3:36])([CH3:35])[O:3][C@H:4]1[CH2:27][C@@:26]2([CH3:28])[C@@H:15]([CH2:16][CH2:17][C@:18]2(OC(=O)C)[C:19](=[O:25])[CH2:20][O:21][C:22](=[O:24])[CH3:23])[C@H:14]2[C@H:5]1[C@:6]1([CH3:34])[C:11]([CH2:12][CH2:13]2)=[CH:10][C:9](=[O:33])[CH:8]=[CH:7]1.C([O-])(=O)C.[K+]>CN(C)C=O>[CH3:36][Si:2]([CH3:1])([CH3:35])[O:3][C@H:4]1[CH2:27][C@@:26]2([CH3:28])[C@@H:15]([CH2:16][CH:17]=[C:18]2[C:19](=[O:25])[CH2:20][O:21][C:22](=[O:24])[CH3:23])[C@H:14]2[C@H:5]1[C@:6]1([CH3:34])[C:11]([CH2:12][CH2:13]2)=[CH:10][C:9](=[O:33])[CH:8]=[CH:7]1

Participants

4

Reactant 2

HCID 517044Potassium AcetateHCID 22798522HCID 22798522, compound

Product 1

HCID 22798535HCID 22798535, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

4 g of 11β-trimethylsiloxy-17α,21-diacetoxypregna-1,4-diene-3,20-dione (from Example 30) was treated with potassium acetate and dimethylformamide exactly as described in Example 28. There was obtained 11β-trimethylsiloxy-21-acetoxypregna-1,4,16-triene-3,20-dione (compound 55).

Sources & evidence

ORD record
ord-4c6d7da272c8424aa4f0bda77fd4b31e
Source dataset
uspto-grants-1977_07
Patent number
US04036831

Reaction notes

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