Oxalic Acid → HCID 21424093, compound

HRID 259311Notes

Reaction equation

HRID 259311 reaction equation
[C:1]12([CH:11]([O:18][CH2:19][C:20]3[CH:25]=[CH:24][C:23]([Cl:26])=[CH:22][C:21]=3[Cl:27])[CH2:12][N:13]3[CH:17]=[CH:16][N:15]=[CH:14]3)[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2.[C:28]([OH:33])(=[O:32])[C:29]([OH:31])=[O:30]>C(OCC)(=O)C>[C:28]([OH:33])(=[O:32])[C:29]([OH:31])=[O:30].[C:1]12([CH:11]([O:18][CH2:19][C:20]3[CH:25]=[CH:24][C:23]([Cl:26])=[CH:22][C:21]=3[Cl:27])[CH2:12][N:13]3[CH:17]=[CH:16][N:15]=[CH:14]3)[CH2:2][CH:3]3[CH2:4][CH:5]([CH2:6][CH:7]([CH2:9]3)[CH2:8]1)[CH2:10]2

Participants

4

Reactant 2

HCID 971Oxalic AcidHCID 21424035HCID 21424035, compound

Product 1

HCID 21424093HCID 21424093, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

A solution of 200 g. of 1-[2-(1-adamantyl)-2-(2,4-dichlorobenzyloxy)ethyl]imidazole in 20 ml. ethyl acetate is acidified with etheral oxalic acid. The product which precipitates is filtered off and recrystallized from methanol/acetone to yield 1-[2-(1-adamantyl)-2-(2,4-dichlorobenzyloxy)ethyl]imidazole oxalate, decomp. 203.5°-205.5° C.

Workup

  1. customThe product which precipitates
  2. filtrationis filtered off
  3. customrecrystallized from methanol/acetone

Sources & evidence

ORD record
ord-31fb16c42b2247e69b9846413cc7c63c
Source dataset
uspto-grants-1977_07
Patent number
US04036975

Reaction notes

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