Potassium Carbonate → HCID 21424034, compound

HRID 259312Notes

Reaction equation

HRID 259312 reaction equation
[N+]([O-])(O)=O.[C:5]12([CH:15]([S:22][C:23]3[CH:28]=[CH:27][C:26]([Cl:29])=[C:25]([Cl:30])[CH:24]=3)[CH2:16][N:17]3[CH:21]=[CH:20][N:19]=[CH:18]3)[CH2:14][CH:9]3[CH2:10][CH:11]([CH2:13][CH:7]([CH2:8]3)[CH2:6]1)[CH2:12]2.C(=O)([O-])[O-].[K+].[K+]>ClCCl>[C:5]12([CH:15]([S:22][C:23]3[CH:28]=[CH:27][C:26]([Cl:29])=[C:25]([Cl:30])[CH:24]=3)[CH2:16][N:17]3[CH:21]=[CH:20][N:19]=[CH:18]3)[CH2:6][CH:7]3[CH2:8][CH:9]([CH2:10][CH:11]([CH2:13]3)[CH2:12]1)[CH2:14]2

Participants

4

Reactant 2

HCID 11430Potassium CarbonateHCID 70632852HCID 70632852, compound

Product 1

HCID 21424034HCID 21424034, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A suspension of 1 g. of 1-[2-(1-adamantyl)-2-(3,4-dichlorophenylthio)ethyl]imidazole nitrate in 100 ml. of dichloromethane is treated with excess aqueous potassium carbonate until a pH of about 11 is obtained. Thereafter, the suspension is shaken until a solution is obtained. The organic phase is then separated, washed with water, dried over magnesium sulfate and evaporated to dryness to yield 1-[2-(1-adamantyl)-2-(3,4-dichlorophenylthio)ethyl]imidazole.

Workup

  1. additionA suspension of 1 g
  2. customis obtained
  3. customis obtained
  4. customThe organic phase is then separated
  5. washwashed with water
  6. dry with materialdried over magnesium sulfate
  7. customevaporated to dryness

Sources & evidence

ORD record
ord-8710b0f7d22b4b99a95dcb9bf9ed86bc
Source dataset
uspto-grants-1977_07
Patent number
US04036975

Reaction notes

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