反应详情

温度

100 °C

A suspension of ethyl 3-phenylsulfonyl-5-chloroindole-2-carboxylate (596 mg, 1.64 mmol) in aqueous conc. ammonium hydroxide (10 mL) containing ammonium chloride (28 mg) was heated at 100° C. for 3 hours in a sealed screw-top tube. The sealed tube was cooled in an ice bath as product crystallized out. The product was collected by filtration, rinsed with ice water, and dried to give the product, mp 253°-254° C.

1. temperatureThe sealed tube was cooled in an ice bath as product
2. customcrystallized out
3. filtrationThe product was collected by filtration
4. washrinsed with ice water
5. customdried
6. customto give the product, mp 253°-254° C.