p-Toluenesulfonic acid → HCID 22924282, compound

HRID 260596Notes

Reaction equation

HRID 260596 reaction equation
[C:1]([O:4][CH2:5][C:6]([CH3:10])([CH2:8][OH:9])[CH3:7])(=[O:3])[OH:2].[C:11]1(C)[CH:16]=[CH:15][C:14](S(O)(=O)=O)=[CH:13][CH:12]=1>C(O)CCCCC>[C:1](=[O:2])([O:4][CH2:5][C:6]([CH3:10])([CH3:7])[CH2:8][OH:9])[O:3][CH2:15][CH2:16][CH2:11][CH2:12][CH2:13][CH3:14]

Participants

4

Reactant 2

HCID 6101p-Toluenesulfonic acidHCID 21943848HCID 21943848, compound

Product 1

HCID 22924282HCID 22924282, compound

Reagents, catalysts & solvents 1

HCID 81031-HexanolSolvent

Conditions

Temperature
100 °C

Procedure

3.9 g of neopentyl glycol carbonate was dissolved in 5.0 g of n-hexanol and 0.075 g of p-toluenesulfonic acid was added to the solution. The mixture was heated at 100° C. for 20 minutes. After the reaction, the mixture was evaporated in vacuo to remove unreacted n-hexanol and then filtered to remove unreacted neopentyl glycol carbonate. n-Hexyl 2,2-dimethyl- 3-hydroxypropyl carbonate was obtained.

Workup

  1. customAfter the reaction
  2. customthe mixture was evaporated in vacuo
  3. customto remove unreacted n-hexanol
  4. filtrationfiltered
  5. customto remove unreacted neopentyl glycol carbonate

Sources & evidence

ORD record
ord-188ae209a2be4d4ea02893be4f82db0a
Source dataset
uspto-grants-1996_06
Patent number
US05527968

Reaction notes

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