Allylamine → HCID 20395264, compound

HRID 261184Notes

Reaction equation

HRID 261184 reaction equation
[CH3:1][N:2]1[C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=2[O:5][CH:4]([C:12]([OH:14])=O)[CH2:3]1.[CH2:15]([NH2:18])[CH:16]=[CH2:17]>C(O)C>[CH3:1][N:2]1[C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=2[O:5][CH:4]([C:12]([NH:18][CH2:15][CH:16]=[CH2:17])=[O:14])[CH2:3]1

Participants

4

Reactant 2

HCID 7853AllylamineHCID 108454494-Methyl-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylic acid

Product 1

HCID 20395264HCID 20395264, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of 1.1 g of 2A, and 5 ml of 2-propenamine in 25 ml of ethanol was refluxed for 16 hours. The solvent and excess amine were stripped off and the residue was passed through a silica gel column using Solvent No. 3 as eluent. The solvent was stripped off to give 2, as light yellow liquid, boiling point not determined.

Workup

  1. customto give 2

Sources & evidence

ORD record
ord-5c4d0229bff84cfbaa7e42bab1cec11c
Source dataset
uspto-grants-1979_08
Patent number
US04164576

Reaction notes

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