Allylamine → HCID 20395266, compound

HRID 261187Notes

Reaction equation

HRID 261187 reaction equation
Cl.[CH3:2][C:3]1[CH:4]=[CH:5][C:6]2[O:11][CH:10]([C:12]([OH:14])=O)[CH2:9][NH:8][C:7]=2[CH:15]=1.[CH2:16]([NH2:19])[CH:17]=[CH2:18]>C(O)C>[CH3:2][C:3]1[CH:4]=[CH:5][C:6]2[O:11][CH:10]([C:12]([NH:19][CH2:16][CH:17]=[CH2:18])=[O:14])[CH2:9][NH:8][C:7]=2[CH:15]=1

Participants

4

Reactant 2

HCID 7853AllylamineHCID 70608080HCID 70608080, compound

Product 1

HCID 20395266HCID 20395266, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

42.4 g of 4A and 38 g of 2-propenamine were mixed in 165 ml of ethanol and the mixture was stirred at room temperature for 90 hours. The solvent was removed under reduced pressure. The residue was partitioned between ether and water. The ether solution was dried (MgSO4), about half the solvent was evaporated, and solid which formed was filtered, then dried under reduced pressure to give 4, mp: 113°-115° C.

Workup

  1. customThe solvent was removed under reduced pressure
  2. customThe residue was partitioned between ether and water
  3. dry with materialThe ether solution was dried (MgSO4)
  4. customabout half the solvent was evaporated
  5. customsolid which formed
  6. filtrationwas filtered
  7. customdried under reduced pressure
  8. customto give 4, mp: 113°-115° C.

Sources & evidence

ORD record
ord-7bdbc48abc8b41ad9d12a0ca708c731d
Source dataset
uspto-grants-1979_08
Patent number
US04164576

Reaction notes

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