反应详情

To a stirred suspension of 6.15 g of pyridinium chlorochromate (Tetrahedron Letters, 1975, 2647) in 20 ml of methylene chloride is added 450 mg of sodium acetate. After 5 minutes a solution of 3.64 g of 4-hydroxy-1-iodo-trans-1-octene in 15 ml of methylene chloride is added in one portion. The dark mixture is stirred at room temperatue for 75 minutes, diluted with 50 ml of ether, and decanted. The solid sludge is washed repeatedly with ether and decanted. The combined solutions are percolated through Florisil. The solution is concentrated to give an orange liquid, pmr spectrum (CDCl3): 3.20 (d, j=7 cps, =CHCH2CO).

1. customdecanted
2. washThe solid sludge is washed repeatedly with ether
3. customdecanted
4. concentrationThe solution is concentrated
5. customto give an orange liquid, pmr spectrum (CDCl3)