反应详情

95 g of 2,6-dichlorobenzamide are suspended in from 250 to 300 ml of dry methylene chloride. After the addition of 56 ml of oxalyl chloride the mixture is slowly heated to boiling point, at which temperature the starting material rapidly dissolves with a strong evolution of hydrochloric acid. After boiling for from 15-18 hours the mixture is concentrated by evaporation in a vacuum. The resulting 2,6-dichlorobenzoylisocyanide is used for the next reaction step without further purification.

1. temperatureis slowly heated
2. customAfter boiling for from 15-18 hours
3. concentrationis concentrated by evaporation in a vacuum
4. customThe resulting 2,6-dichlorobenzoylisocyanide is used for the next reaction step without further purification