Hydrogen Sulfide → HCID 21319836, compound

HRID 262037Notes

Reaction equation

HRID 262037 reaction equation
[CH3:1][C:2]1[S:3][C:4]([C:8]#[N:9])=[C:5]([NH2:7])[N:6]=1.CN(C)C=O.[SH2:15]>C(N(CC)CC)C>[CH3:1][C:2]1[S:3][C:4]([C:8](=[S:15])[NH2:9])=[C:5]([NH2:7])[N:6]=1

Participants

5

Reactant 3

HCID 402Hydrogen SulfideHCID 6228DimethylformamideHCID 21319840HCID 21319840, compound

Product 1

HCID 21319836HCID 21319836, compoundYield 58%

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

5.5 parts of 2-methyl-4-amino-5-cyano-thiazole in 50 parts of dimethylformamide and 10 parts of triethylamine are reacted with 3 parts of hydrogen sulfide as described in Example 1(a). 4.0 parts of 2-methyl-4-amino-5-thiocarbamoylthiazole (58% of theory) of melting point 209°-213° C. are obtained.

Sources & evidence

ORD record
ord-eae91aedd3c240b083970e1d69793fad
Source dataset
uspto-grants-1979_05
Patent number
US04153607

Reaction notes

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