Ethyl isocyanate → HCID 21318676, compound

HRID 262405Notes

Reaction equation

HRID 262405 reaction equation
Cl.[S:2]1[CH:6]=[CH:5][C:4]2[CH2:7][CH2:8][CH2:9][CH:10]([NH2:11])[C:3]1=2.C(N(CC)CC)C.[CH2:19]([N:21]=[C:22]=[O:23])[CH3:20]>C(Cl)Cl>[CH2:19]([NH:21][C:22]([NH:11][CH:10]1[C:3]2[S:2][CH:6]=[CH:5][C:4]=2[CH2:7][CH2:8][CH2:9]1)=[O:23])[CH3:20]

Participants

5

Reactant 3

HCID 8022Ethyl isocyanateHCID 8471TriethylamineHCID 21318680HCID 21318680, compound

Product 1

HCID 21318676HCID 21318676, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Equivalent amounts of 4,5,6,7-tetrahydrobenzo[b]thiophen-7-amine hydrochloride, triethylamine, and ethyl isocyanate in methylene chloride are stirred at room temperature for an hour and then heated to reflux for half an hour. The product is collected, washed well with water, and dried to afford the title compound.

Workup

  1. temperatureheated
  2. temperatureto reflux for half an hour
  3. customThe product is collected
  4. washwashed well with water
  5. customdried

Sources & evidence

ORD record
ord-6a571396d37945598b082d1038a8df89
Source dataset
uspto-grants-1979_05
Patent number
US04154740

Reaction notes

Loading…