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HRID262965

反应详情

EQUATION

反应方程式

HRID 262965 的结构方程式

REACTANTS

反应物

3
结构：c1ccccc1
HCID241

Benzene

C6H6

结构：Cc1ccc(S(=O)(=O)O)cc1
HCID6101

4-Methylbenzenesulfonic acid

C7H8O3S

结构：C[C@H]1CC(=O)C[C@@H]2CC[C@H]3[C@@H]4CC[C@H](O)[C@@]4(C)CC[C@@H]3[C@]21C
HCID15020

Mesterolone

C20H32O2

PRODUCTS

生成物

1
结构：C[C@H]1CC2(C[C@@H]3CC[C@H]4[C@@H]5CC[C@H](O)[C@@]5(C)CC[C@@H]4[C@]31C)OCCO2
HCID13020861

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCOCC
溶剂HCID3283

Diethyl Ether

C4H10O

PROCEDURE

实验过程

50 g of 17β-hydroxy-1α-methyl-5α-androstan-3-one were heated at reflux in 1000 ml of absolute benzene, 125 ml of ethylenegycol and 1.25 g of p-toluenesulphonic acid for 7 hours while stirring under a water separator. The solution was then diluted with ether, washed with sodium hydrogen carbonate solution and water, dried and evaporated to dryness. 55 g of 3,3-ethylenedioxy-17β-hydroxy-1α-methyl-5α-androstane were obtained.

WORKUP

后处理

  1. washwashed with sodium hydrogen carbonate solution and water
  2. customdried
  3. customevaporated to dryness