反应详情

2.76 g of sodium are dissolved in 100 ml of anhydrous ethanol and 20.8 g (0.120 mol) of p-bromophenol are added. 22.1 g (0.132 mol) of ethyl bromoacetate are run into this solution over the course of 20 minutes and the mixture is then heated under reflux for 1 hour. The ethanol is driven off under reduced pressure and the residue is dissolved in diethyl ether; after washing with water and then with a potassium carbonate solution, and evaporating the solvent, 30.2 g of a white powder are obtained. After purification of this product by crystallisation from petroleum ether, 23 g of a white, water-insoluble powder are obtained.

1. customare run into this solution over the course of 20 minutes
2. temperaturethe mixture is then heated
3. temperatureunder reflux for 1 hour
4. washafter washing with water
5. customwith a potassium carbonate solution, and evaporating the solvent, 30.2 g of a white powder
6. customare obtained
7. customAfter purification of this product
8. customby crystallisation from petroleum ether, 23 g of a white, water-insoluble powder
9. customare obtained