Phenethylamine → HCID 20298677, compound

HRID 263106Notes

Reaction equation

HRID 263106 reaction equation
[CH3:1][N:2]([CH3:17])[CH2:3][CH2:4][CH2:5][O:6][C:7]1[CH:14]=[CH:13][C:12]([O:15][CH3:16])=[CH:11][C:8]=1[CH:9]=O.[CH2:18]([NH2:26])[CH2:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>C1(C)C=CC=CC=1>[CH3:1][N:2]([CH2:3][CH2:4][CH2:5][O:6][C:7]1[CH:14]=[CH:13][C:12]([O:15][CH3:16])=[CH:11][C:8]=1[CH:9]=[N:26][CH2:18][CH2:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)[CH3:17]

Participants

4

Reactant 2

HCID 1001PhenethylamineHCID 20298674HCID 20298674, compound

Product 1

HCID 20298677HCID 20298677, compoundYield 83%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

2-[3-(Dimethylamino)propoxy]-5-methoxybenzaldehyde (33.5 g) and 17.4 g of phenethylamine are reacted in 140 ml of toluene following the procedure described in Example 1B yielding 39.9 g of the title compound, boiling point 197°-202° C. at 0.2-0.3 mm of Hg.

Sources & evidence

ORD record
ord-ccb7a478b5f94a348865c0ef7b3fc992
Source dataset
uspto-grants-1979_05
Patent number
US04156079

Reaction notes

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