Hydrochloric Acid → HCID 21316373, compound

HRID 263174Notes

Reaction equation

HRID 263174 reaction equation
[C:1]([CH2:3][CH2:4][N:5]([CH2:8][CH2:9][CH2:10][OH:11])[CH:6]=[O:7])#[N:2].[ClH:12].[H][H]>[Pt].O>[Cl-:12].[CH:6]([N:5]([CH2:4][CH2:3][CH2:1][NH3+:2])[CH2:8][CH2:9][CH2:10][OH:11])=[O:7]

Participants

6

Reactant 3

HCID 313Hydrochloric AcidHCID 21316366HCID 21316366, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 21316373HCID 21316373, compound

Reagents, catalysts & solvents 2

HCID 23939PlatinumCatalystHCID 962WaterSolvent

Procedure

A solution of 15.6 g. (100 mmoles) of 3-[N-(2-cyanoethyl)-N-formylamino]-propanol in 225 ml. of water is treated with 100 ml. of 1 N hydrochloric acid and reduced over 3.8 g. of platinum at room temperature and 40 psi of hydrogen. The reaction mixture is filtered and concentrated under reduced pressure yielding 3-[N'-formyl-N'-(3-hydroxypropyl)amino]-1-propanaminium chloride.

Workup

  1. customat room temperature
  2. filtrationThe reaction mixture is filtered
  3. concentrationconcentrated under reduced pressure

Sources & evidence

ORD record
ord-64a1cd66aed54153895bcc9c0e889522
Source dataset
uspto-grants-1979_05
Patent number
US04156693

Reaction notes

Loading…