反应详情

3.1 g (0.0254 moles) of salicylic aldehyde are dissolved in 30 ml of anhydrous toluene and 8.1 g (0.025 moles) of N-methyl-carbamic acid-pentachlorophenyl-ester are added under stirring at room temperature, whereafter 2.6 g (0.0257 moles) of triethylamine are added to the mixture under stirring. During the addition of the triethylamine an elevation of the temperature of about 2°-5° C. may be observed. The reaction mixture is stirred at 25°-30° C. for 2 hours, after about 1 hour the reaction mixture becomes clear. The unreacted active ester is filtered, the toluene is removed from the filtrate and the residual oily substance is recrystallized from a three-fold amount of diisopropylether. 2-methyl-carbamoyloxy-benzaldehyde is obtained. Mp.: 128°-132° C.

1. additionare added to the mixture
2. stirringThe reaction mixture is stirred at 25°-30° C. for 2 hours, after about 1 hour the reaction mixture
3. filtrationThe unreacted active ester is filtered
4. customthe toluene is removed from the filtrate
5. customthe residual oily substance is recrystallized from a three-fold amount of diisopropylether