huagongshe.com
HRID263973

反应详情

EQUATION

反应方程式

HRID 263973 的结构方程式

REACTANTS

反应物

3
结构：O=Cc1ccc(Cl)cc1
HCID7726

4-Chlorobenzaldehyde

C7H5ClO

结构：COC(=O)CC(C)=O
HCID7757

Methyl acetoacetate

C5H8O3

结构：CC(=O)C=C(C)N
HCID136873

4-Amino-3-penten-2-one

C5H9NO

PRODUCTS

生成物

1
结构：COC(=O)C1=C(C)NC(C)=C(C(C)=O)C1c1ccc(Cl)cc1
HCID15337221

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC(C)O
溶剂HCID3776

Isopropanol

C3H8O

PROCEDURE

实验过程

5.64 g (40 mmol) of 4-chlorobenzaldehyde, 4.0 g (40 mmol) of 4-aminopent-3-en-2-one and 4.6 g (40 mmol) of methyl acetoacetate are heated to reflux for 12 h in 100 ml of isopropanol. The reaction mixture is allowed to cool and is concentrated. 1.85 g of the title compound crystallize from Et2O.

WORKUP

后处理

  1. temperatureto cool
  2. concentrationis concentrated
  3. custom1.85 g of the title compound crystallize from Et2O