Selenium Dioxide → 8-methyl-3-methylthio-11H-s-triazolo[3,4-b][3]benzazepin-11-one

HRID 26510Notes

Reaction equation

[CH3:1][C:2]1[CH:3]=[CH:4][C:5]2[CH2:11][C:10]3=[N:12][N:13]=[C:14]([S:15][CH3:16])[N:9]3[CH:8]=[CH:7][C:6]=2[CH:17]=1.[Se](=O)=[O:19]>>[CH3:1][C:2]1[CH:3]=[CH:4][C:5]2[C:11](=[O:19])[C:10]3=[N:12][N:13]=[C:14]([S:15][CH3:16])[N:9]3[CH:8]=[CH:7][C:6]=2[CH:17]=1

Participants

Reactant 2

HCID 24007Selenium Dioxide

HCID 213233378-methyl-3-methylthio-11H-s-triazolo[3,4-b][3]benzazepine

Product 1

HCID 213235358-methyl-3-methylthio-11H-s-triazolo[3,4-b][3]benzazepin-11-one

Procedure

By a procedure similar to that described in Examples 13, the reaction of 8-methyl-3-methylthio-11H-s-triazolo[3,4-b][3]benzazepine with selenium dioxide gave 8-methyl-3-methylthio-11H-s-triazolo[3,4-b][3]benzazepin-11-one as crystals. Recrystallization from methanol yielded colorless platelets melting at 178°-179° C.

Sources & evidence

ORD record: ord-6f8d947953a24750bf9d8f76536b615e
Source dataset: uspto-grants-1979_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04150139

Reaction notes

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