反应详情

Following a procedure similar to that described in Preparation 42(i), 4.00 g of diethyl 2-ethylimidazole-4,5-dicarboxylate were benzylated, using 2.20 ml of benzyl bromide. The product was purified by column chromatography through silica gel, using a 1:1 by volume mixture of methylene chloride and ethyl acetate as the eluent, to give 5.19 g of the title compound as a syrup.

1. customThe product was purified by column chromatography through silica gel
2. additionby volume mixture of methylene chloride and ethyl acetate as the eluent