1-Bromooctane → HCID 4148530, compound

HRID 265373Notes

Reaction equation

HRID 265373 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[NH:9][C:10]([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)=[C:11]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[N:12]=2)=[CH:4][CH:3]=1.Br[CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH3:33]>>[CH2:26]([O:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[NH:12][C:11]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)=[C:10]([C:19]3[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=3)[N:9]=2)=[CH:6][CH:7]=1)[CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH3:33]

Participants

3

Reactant 2

HCID 81401-BromooctaneHCID 3521444-(4 5-Diphenyl-2-imidazolyl)phenol*

Product 1

HCID 4148530HCID 4148530, compoundYield 63.1%

Procedure

2-(4-Hydroxyphenyl)-4,5-diphenylimidazole (5 g) (J. Org. Chem., 1964, 29, 1926) was reacted with 8-bromooctane (6.2 g) in a method similar to Example 9. Work-up and recrystallisation from ethanol and water gave 2-(4-octyloxyphenyl)-4,5-diphenylimidazole (4.29 g, 63%) as a white solid, m.p. 178°. Found: C, 82.31; H, 7.66; N, 6.73%; C29H32N2O requires C, 82.04; H, 7.60; N, 6.60%.

Workup

  1. customrecrystallisation from ethanol and water

Sources & evidence

ORD record
ord-63253a76e5e74da2a9181d4035d43177
Source dataset
uspto-grants-1997_07
Patent number
US05648373

Reaction notes

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