m-Chloroperbenzoic acid → HCID 15392139, compound

HRID 266452Notes

Reaction equation

HRID 266452 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[N:3][C:2]=1[S:7]([CH2:9][N:10]1[C:20](=[O:21])[C:19]2[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=2)[S:11]1(=[O:13])=[O:12])=[O:8].ClC1C=CC=C(C(OO)=[O:30])C=1>>[N:3]1[CH:4]=[CH:5][CH:6]=[N:1][C:2]=1[S:7]([CH2:9][N:10]1[C:20](=[O:21])[C:19]2[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=2)[S:11]1(=[O:13])=[O:12])(=[O:30])=[O:8]

Participants

3

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 21758505HCID 21758505, compound

Product 1

HCID 15392139HCID 15392139, compound

Procedure

Following a procedure similar to that described in Example 32A, 0.75 g (0.0023 mol) of 2-(2-pyrimidinylsulfinylmethyl)saccharin was oxidized with 0.4 g (0.0023 mol) of 3-chloroperbenzoic acid in 50 ml of MDC and the product recrystallized from 75:25 acetonitrile:ethanol to give 2-(2-pyrimidinylsulfonylmethyl)saccharin, mp 225°-227° C.

Workup

  1. customthe product recrystallized from 75:25 acetonitrile

Sources & evidence

ORD record
ord-5bd77b62f119411f840ea58553bdc4c3
Source dataset
uspto-grants-1997_07
Patent number
US05650422

Reaction notes

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