Ethanol → HCID 657774, compound

HRID 266694Notes

Reaction equation

HRID 266694 reaction equation
[NH2:1][C:2]1[CH:8]=[CH:7][CH:6]=[CH:5][C:3]=1[NH2:4].C(OC([CH:14]1[CH2:18][CH2:17][CH2:16][C:15]1=O)=O)C.O.[CH2:21]([OH:23])C>C1(C)C(C)=CC=CC=1>[C:14]1([N:1]2[C:2]3[CH:8]=[CH:7][CH:6]=[CH:5][C:3]=3[NH:4][C:21]2=[O:23])[CH2:18][CH2:17][CH2:16][CH:15]=1

Participants

6

Reactant 4

HCID 702EthanolHCID 962WaterHCID 7243O-PhenylenediamineHCID 69136Ethyl 2-oxocyclopentanecarboxylate

Product 1

HCID 657774HCID 657774, compound

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

100 mmol of 2-aminoaniline and 135 mmol of 2-ethoxycarbonylcyclopentanone in 50 ml of xylene are brought to reflux for 5 hours, the water and the ethanol formed being removed with the aid of a Dean and Stark apparatus. After cooling, the expected product crystallizes and it is then filtered, washed with xylene and then with hexane and then dried.

Workup

  1. temperatureto reflux for 5 hours
  2. custombeing removed with the aid of a Dean and Stark apparatus
  3. temperatureAfter cooling
  4. customthe expected product crystallizes
  5. filtrationit is then filtered
  6. washwashed with xylene
  7. dry with materialwith hexane and then dried

Sources & evidence

ORD record
ord-7ac6d9fe98f1498ba392bc96ea506c11
Source dataset
uspto-grants-1997_07
Patent number
US05652246

Reaction notes

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