Phthalimide → HCID 21555871, compound

HRID 267433Notes

Reaction equation

HRID 267433 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([N:16]2[C:20]([CH3:21])=[CH:19][N:18]=[C:17]2[CH2:22]O)=[C:6]([CH:15]=1)[C:7]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)=[O:8].[C:24]1(=[O:34])[NH:28][C:27](=[O:29])[C:26]2=[CH:30][CH:31]=[CH:32][CH:33]=[C:25]12.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.N(C(OCC)=O)=NC(OCC)=O>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([N:16]2[C:20]([CH3:21])=[CH:19][N:18]=[C:17]2[CH2:22][N:28]2[C:24](=[O:34])[C:25]3=[CH:33][CH:32]=[CH:31][CH:30]=[C:26]3[C:27]2=[O:29])=[C:6]([CH:15]=1)[C:7]([C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=1)=[O:8]

Participants

5

Reactant 4

HCID 6809PhthalimideHCID 11776TriphenylphosphineHCID 220568ethyl N-ethoxycarbonyliminocarbamateHCID 21555847HCID 21555847, compound

Product 1

HCID 21555871HCID 21555871, compound

Procedure

In the manner given in Example 17, 5-chloro-2-[5-methyl-2-(hydroxymethyl)imidazol-1-yl]benzophenone is treated with phthalimide and triphenylphosphine and finally with diethyl azodicarboxylate to give 5-chloro-2-[5-methyl-2-(phthalimidomethyl)imidazol-1-yl]benzophenone.

Sources & evidence

ORD record
ord-3e87a5a62fb74236ac6081a46119c4d5
Source dataset
uspto-grants-1976_03
Patent number
US03941803

Reaction notes

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