Phthalimide → HCID 21555880, compound

HRID 267440Notes

Reaction equation

HRID 267440 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8](=[O:22])[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[N:15]1[CH:19]=[CH:18][N:17]=[C:16]1[CH2:20]O.[C:23]1(=[O:33])[NH:27][C:26](=[O:28])[C:25]2=[CH:29][CH:30]=[CH:31][CH:32]=[C:24]12.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.N(C(OCC)=O)=NC(OCC)=O>>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8](=[O:22])[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[N:15]1[CH:19]=[CH:18][N:17]=[C:16]1[CH2:20][N:27]1[C:26](=[O:28])[C:25]2=[CH:29][CH:30]=[CH:31][CH:32]=[C:24]2[C:23]1=[O:33]

Participants

5

Reactant 4

HCID 6809PhthalimideHCID 11776TriphenylphosphineHCID 220568ethyl N-ethoxycarbonyliminocarbamateHCID 21555858HCID 21555858, compound

Product 1

HCID 21555880HCID 21555880, compound

Procedure

In the manner given in Example 17, 2'-chloro-2-[2-(hydroxymethyl)imidazol-1-yl]benzophenone is treated with phthalimide and triphenylphosphine and finally with diethyl azodicarboxylate to give 2'-chloro-2-[2-(phthalimidomethyl)imidazol-1-yl]benzophenone.

Sources & evidence

ORD record
ord-26e4d4b1e0c34eb5a9239b8abd6f5627
Source dataset
uspto-grants-1976_03
Patent number
US03941803

Reaction notes

Loading…